MR Cardiac Perfusion Analysis

This project focused on analyzing contrast enhancement curves from a region of interest in MR time-series perfusion studies. The study was to automate the analysis of the health of the heart. The analysis was performed using the dual-bolus technique where two infusions for contrast agent were administered. To calculate the flow in the myocardium a number of key time points along the contrast enhancement curves were required to be selected. The process of the key time point selection was automated utilizing signal analysis.

Publications

  • L. Hsu, D. Mirota, C. H. Lorenz, G. Funka-Lea, and A. E. Arai, "Automated Determination of First-Pass Contrast Enhancement Timing Facilitates Semiquantitative And Quantitative Myocardial Perfusion Measurements," in Moderated Posters Session II, 2007, pp. 327-333.
    bibtex Go to document
    @INPROCEEDINGS{Hsu2007,
      author = {Hsu, Li-Yueh and Mirota, Daniel and Lorenz, Christine H. and Funka-Lea, Gareth and Arai, Andrew E.},
      title = {Automated Determination of First-Pass Contrast Enhancement Timing Facilitates Semiquantitative And Quantitative Myocardial Perfusion Measurements},
      booktitle = {Moderated Posters Session II},
      year = {2007},
      volume = {9},
      number = {2},
      pages = {327-333},
      organization = {Society for Cardiovascular Magnetic Resonance},
      file = {Hsu2007a.pdf:Hsu2007a.pdf:PDF},
      journal = {Journal of Cardiovascular Magnetic Resonance},
      owner = {dmirota},
      timestamp = {2007.10.31}
    }
  • L. Hsu, F. E. Mordini, D. Mirota, G. Funka-Lea, and A. E. Arai, "Myocardial Blood Flow Can Be Quantified in Sub-Gram Regions of Interest in Clinical MR First Pass Perfusion," in International Society of Magnetic Resonance in Medicine, 2006.
    bibtex Go to document
    @INPROCEEDINGS{Hsu2006,
      author = {Hsu, Li-yueh and Mordini, Federico E. and Mirota, Daniel and Funka-Lea, Gareth and Arai, Andrew E.},
      title = {Myocardial Blood Flow Can Be Quantified in Sub-Gram Regions of Interest in Clinical MR First Pass Perfusion},
      booktitle = {International Society of Magnetic Resonance in Medicine},
      year = {2006},
      file = {03572.pdf:03572.pdf:PDF},
      owner = {dmirota},
      timestamp = {2007.10.31}
    }